mu/mu4e are known to work on a wide variety of Unix- and Unix-like systems,
including many Linux distributions, OS X and FreeBSD, and even on MS-Windows (with Cygwin).
emacs 23 or 24 (recommended) is required, as well as Xapian12 and GMime13.
mu has optional support for the Guile 2.x (Scheme) programming language. There are also some GUI-tools, which require GTK+ 3.x and Webkit.
If you intend to compile mu yourself, you need to have the typical development tools,
such as C and C++ compilers (both
clang should work), GNU
make, and the development packages for GMime, GLib and Xapian.
Optionally (if you use them), you also need the development packages for GTK+, Webkit and